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Five S&P 500 Names Hit New Highs Amid Market Decline

By Stocks Desk · 2026-09-17 · 2 min read
A glass microscope slide resting on a laboratory bench next to a test tube containing clear liquid
Illustration: Tradingbird

Thermo Fisher, Marathon, Valero, and two smaller peers reached 52-week peaks despite a 2.4% monthly drop in the broader index.

Five S&P 500 constituents reached 52-week highs on September 16, a date when the broader index fell 2.4% over the preceding month. The group is split between healthcare and energy, with Thermo Fisher Scientific leading by market capitalization at $240.6 billion. Marathon Petroleum and Valero Energy follow, each valued near $120 billion, while Danaher and Revvity round out the list with smaller market caps.

According to data from GN stocks/sp500, these five names represent the entire set of S&P 500 stocks trading at their highest levels in the past year. The performance metrics reveal distinct growth profiles. Thermo Fisher posted a 37.1% gain over the last year, while the energy majors displayed significantly higher one-year returns, with Valero up 161.4% and Marathon up 133.9%.

Energy Majors Lead One-Year Gains

Valero Energy and Marathon Petroleum recorded the strongest annual performance among the five. Valero gained 161.4% over the last twelve months, accompanied by a 16.2% rise in the past month. Marathon Petroleum followed with a 133.9% one-year increase and a 15.9% monthly gain. Both companies also posted positive one-week and one-day changes, reflecting sustained momentum in the energy sector.

Thermo Fisher Scientific, the largest company on the list, showed a more moderate one-year return of 37.1%. However, it delivered a 10.8% increase over the last month and a 7.1% gain over the week. Danaher Corp completed the healthcare segment with a 39.2% one-year return and a 4.9% monthly increase, showing steady but less explosive growth compared to its energy counterparts.

Revvity Trades At Premium Valuation

Revvity recorded the strongest one-month performance on the list, rising 25.4%. This rapid appreciation aligns with its high valuation multiple of 68.5 times trailing earnings. The company’s revenue grew 4.1% over the last twelve months, and it maintained an operating margin of 12.3%. Its market capitalization stands at $16.26 billion, the smallest among the five high-making stocks.

Price Strength Requires Fundamental Support

Reaching a 52-week high indicates current market sentiment but does not guarantee future performance. The divergence between the high-growth energy names and the premium-valued healthcare firms highlights different risk profiles. Investors must assess whether the underlying business fundamentals, such as cash generation and margin stability, justify the new price levels. A rising price reflects past strength; sustained value depends on the quality of the business operations supporting that run.

Based on reporting by trefis.com, compiled by the Tradingbird desk.

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